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  • Title: Juvenile Polyps with Osseous Metaplasia: Report of Two Pediatric Cases and Review of the Literature.
    Author: Azari-Yam A, Alimadadi H, Safavi M.
    Journal: Fetal Pediatr Pathol; 2022 Feb; 41(1):166-170. PubMed ID: 32406794.
    Abstract:
    BACKGROUND: Osseous metaplasia is considered as a response to insults such as chronic inflammation or mucin extravasation in colorectal polyps. CASE REPORT: we report two cases of osseous metaplasia in juvenile (retention) polyps as incidental histopathological findings in a case of rectal juvenile polyposis and a patient with solitary rectal juvenile polyp. CONCLUSION: Osseous metaplasia can occur in colorectal juvenile polyps and is considered a probable response to mucin extravasation and/or chronic inflammation. The clinical and prognostic significance of osseous metaplasia in these polyps is unknown.
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