These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Gelatin-crosslinked pectin nanofiber mats allowing cell infiltration.
    Author: Shi X, Cui S, Song X, Rickel AP, Sanyour HJ, Zheng J, Hu J, Hong Z, Zhou Y, Liu Y.
    Journal: Mater Sci Eng C Mater Biol Appl; 2020 Jul; 112():110941. PubMed ID: 32409087.
    Abstract:
    Pectin nanofiber mats are promising tissue engineering scaffolds but suffer from poor cell infiltration. In this study, gelatin, a collagen derived cell adhesive protein, was used to crosslink the electrospun nanofibers of periodate oxidized pectin. Cell culture experiment results demonstrated that cells were able to grow into the gelatin-crosslinked pectin nanofiber mats rather than only spread on mat surface. The nanofiber mats showed moderate mechanical strength, with a maximum tensile strength of up to 2.3 MPa, an ultimate tensile strain of up to 15%, and were capable of degrading gradually over 4 weeks or even longer periods in simulated body fluids. Thus, gelatin-crosslinked pectin nanofiber mats hold a great potential for soft tissue regeneration.
    [Abstract] [Full Text] [Related] [New Search]