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  • Title: [Audiologic evaluation of patients with thalassemic syndromes treated with desferrioxamine B].
    Author: Gaini RM, Moretti E, Boffa C, Terzoli S, Carnelli V.
    Journal: Pediatr Med Chir; 1988; 10(5):503-4. PubMed ID: 3241755.
    Abstract:
    Following various articles in literature which have appeared in the last 3 years regarding the neurotoxicity of desferrioxamine B we studied, from the auditory functionality point of view, 95 patients affected with transfusion-dependent thalassemic syndromes, under regular chelation treatment with desferrioxamine B. Our results lead us to conclude that at standard doses, between 40 and 60 mg/Kg/day, desferrioxamine B does not demonstrate a neurotoxicity enough to cause an organic deficit in the auditory sphere, while maintaining therapeutic efficacy.
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