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  • Title: Magnetic resonance imaging in Pelizaeus-Merzbacher disease.
    Author: Shimomura C, Matsui A, Choh H, Funahashi M, Suzuki Y, Tsuchiya K.
    Journal: Pediatr Neurol; 1988; 4(2):124-5. PubMed ID: 3242511.
    Abstract:
    Cranial computed tomography of a boy with clinical characteristics of the classic form of Pelizaeus-Merzbacher disease did not reveal a notable abnormality other than enlarged ventricles. Magnetic resonance imaging, however, demonstrated diffuse changes in the white matter with sparing of scattered small areas, suggesting persistent myelin islands which are a typical neuropathologic finding in Pelizaeus-Merzbacher disease. Magnetic resonance imaging appears more useful than computed tomography in confirming the diagnosis of Pelizaeus-Merzbacher disease.
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