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  • Title: Amniotic fluid lecithin/sphingomyelin ratio in high risk pregnancy.
    Author: Ng HT, Chen CY, Hsieh HM, Leung WY, Ou MC, Tang WL.
    Journal: Proc Natl Sci Counc Repub China B; 1988 Oct; 12(4):247-51. PubMed ID: 3244820.
    Abstract:
    The amniotic fluid lecithin/sphingomyelin (L/S) ratio from 128 cases of high risk pregnancies were measured by using high performance liquid chromatography (HPLC). The L/S ratio was found to be increased in patients with pre-eclampsia, hypertension, intrauterine growth retardation (IUGR), prolonged rupture of membranes (PROM), and twin gestation, but decreased in patients with diabetes from gestational diabetes to class C. In patients with placenta previa, the L/S ratio was not affected.
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