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  • Title: Cargo Binding by Unconventional Myosins.
    Author: Li J, Zhang M.
    Journal: Adv Exp Med Biol; 2020; 1239():21-40. PubMed ID: 32451854.
    Abstract:
    Unconventional myosins are a large superfamily of actin-based molecular motors that use ATP as fuel to generate mechanical motions/forces. The distinct tails in different unconventional myosin subfamilies can recognize various cargoes including proteins and lipids. Thus, they can play diverse roles in many biological processes such as cellular trafficking, mechanical supports, force sensing, etc. This chapter focuses on some recent advances on the structural studies of how unconventional myosins specifically bind to cargoes with their cargo-binding domains.
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