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  • Title: [Selection for a decrease in metastatic potential in a cell population of transplantable rat rhabdomyosarcoma RA-2].
    Author: Guzhova IV, Vakhtin IuB.
    Journal: Tsitologiia; 1988 Dec; 30(12):1482-7. PubMed ID: 3247682.
    Abstract:
    The method of individual cloning was used for checking the reduction of metastatic potential (MP) in cell population of highly malignant rhabdomyosarcoma RA-2. In the course of 15 selection cycles MP was lowered by 10-15 times. These data enabled us to consider the MP value as a quantitative character of malignant cells with low heritability (the mean value of realized heritability coefficient is equal to 0.18).
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