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  • Title: [The possibilities of selecting an adequate therapy of systemic lupus erythematosus based on the results of HLA typing].
    Author: Lesniak OM.
    Journal: Vutr Boles; 1988; 27(6):52-5. PubMed ID: 3247705.
    Abstract:
    In order to find out the most suitable treatment for systemic lupus erythematodes the frequency of various antigens in the locus A and B of the system HLA was examined in various clinical subgroups of patients with systemic lupus erythematodes. A correlation was established between the group of patient treated intensively and the antigens HLA-A11, HLA-B18, HLA-B8. The antigens HLA-B35 and HLA-B5 were associated with the group of patients treated with a moderately intensive treatment for systemic lupus erythematodes. The patients with systemic lupus erythematodes with antigens HLA-A11, HLA-B18 and HLA-B8 should be actively treated from the onset of the disease in order to avoid severe lesions of the kidneys and the CNS and the polysyndrome clinical manifestations.
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