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  • Title: Genetic polymorphisms of the Pmo1 and Pmo2 salivary proteins detected by the modified protein staining method.
    Author: Minaguchi K, Suzuki K.
    Journal: Ann Hum Genet; 1988 Jul; 52(3):177-87. PubMed ID: 3250329.
    Abstract:
    Two polymorphic proteins, Pmo1 and Pmo2, were found in human parotid saliva by modifying the protein staining method of Sung & Smithies (1969). The inheritance of each polymorphism was controlled by a dominant allele at an autosomal locus. This hypothesis was supported by studies in 50 families including 103 children. The gene frequencies were Pmo1+ = 0.308, Pmo1- = 0.692, Pmo2+ = 0.026, Pmo2- = 0.974. The Pmo1 and Pmo2 proteins reacted immunologically with antisera prepared to salivary proline-rich proteins (Pr and Gl). The isoelectric point was in excess of 8.58. These results showed that the Pmo1 and Pmo2 proteins belong to the basic proline-rich proteins in human parotid saliva.
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