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  • Title: Neonatal screening for congenital adrenal hyperplasia using 17-hydroxyprogesterone assay in filter paper blood spots.
    Author: Larsson A, Hagenfeldt L, von Döbeln U, Curstedt T, Gustafsson J, Svensson E.
    Journal: Horm Res; 1988; 30(6):235-40. PubMed ID: 3250925.
    Abstract:
    Screening of infants for congenital adrenal hyperplasia (CAH) using filter paper blood samples collected on the 5th day of life was performed with a radioimmunoassay for 17-hydroxyprogesterone without extraction with organic solvents. A total of 153,000 newborns were screened and 12 cases of CAH were detected (1:12,800). With recall levels related to gestational age, the recall rate could be lowered to 0.05%.
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