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  • Title: Glycerol Preserved Amnion: A Viable Source of Biological Dressing for Superficial Partial Thickness Facial Burns.
    Author: Raza MS, Asif MU, Abidin ZU, Khalid FA, Ilyas A, Tarar MN.
    Journal: J Coll Physicians Surg Pak; 2020 Apr; 30(4):394-398. PubMed ID: 32513359.
    Abstract:
    OBJECTIVES: To evaluate the role of amnion as a biological dressing in superficial partial thickness facial burns. STUDY DESIGN: Randomized controlled trial. PLACE AND DURATION OF STUDY: Jinnah Burn and Reconstructive Surgery Centre, Lahore, from January 2017 to December 2018. METHODS: Sixty two patients with superficial partial thickness facial burns were randomly divided into two groups (A and B). Ointment containing Polymyxin B and Bacitracin was applied in group A (n=28) while amnion was applied in group B (n=34). The patients were monitored for the pain related to burns needing analgesia, time of healing of burns, and cosmetic outcome of the facial scarring over a period of six months. RESULTS: The mean age of the patients was 26.5 ±12.2 years. 39 (62.9%) patients were male and 23 (37.1%) were females. The mean percent total facial surface area burned was 2.7% ±1. None of the patients developed facial wound infections. The average healing time was 6 ±2 days. The mean frequency of analgesia for 3 days of group B was less as compared to group A. infection rate was similar in both groups. No significant difference was observed in VAS score at 1, 3 and 6 month follow up between both groups. CONCLUSION: Amnion is a safe, cost effective and most readily available biological dressing for superficial partial thickness facial burn management. Key Words: Amnion, Facial burn, Biological dressing, Scarring, Partial thickness burn.
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