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Title: Interaction between X-ray and alpha-particle damage in V79 cells. Author: McNally NJ, de Ronde J, Folkard M. Journal: Int J Radiat Biol Relat Stud Phys Chem Med; 1988 Jun; 53(6):917-20. PubMed ID: 3259561. Abstract: V79 cells have been exposed to X-rays or 238Pu alpha-particles or to X-rays following priming alpha-particle doses of 0.5, 2 or 2.5 Gy. The survival curve for exposure to alpha-particles was exponential with a D0 of 0.89 Gy. Following exposure to priming alpha-particle doses the resulting X-ray survival curves had the same slope as the single dose X-ray curve, but a reduced shoulder. For alpha-particle priming doses of 0.5 and 2 Gy this reduction was the same as for the same X-ray doses. 2.5 Gy alpha-particles reduced the subsequent X-ray curve Dq to almost zero. alpha-particles do cause damage capable of interacting with X-ray damage.[Abstract] [Full Text] [Related] [New Search]