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  • Title: Penile Necrosis as a Presenting Sign of Purpura Fulminans Mimicking Fournier's Gangrene.
    Author: Caputo V, Bonoldi E, Rongioletti F.
    Journal: Am J Dermatopathol; 2021 Jan 01; 43(1):e13-e15. PubMed ID: 32675467.
    Abstract:
    We report the case of a 63-year-old white man who, 3 days after stent removal of endoscopic drainage of pancreatic cysts, developed a penile necrosis due to purpura fulminans (PF) that has been misdiagnosed as Fournier's gangrene. Penile necrosis was rapidly followed by a lethal multiorgan failure due to disseminated intravascular coagulopathy (DIC), triggered by the subsequent development of a severe acute pancreatitis. PF describes a rare syndrome involving intravascular thrombosis and hemorrhagic infarction of the skin. Although reports of penile necrosis secondary to various causes are documented in the literature, penile necrosis secondary to PF in the setting of acute pancreatitis is a rare event. Histopathologic studies of the skin showing an occlusive nonvasculitic vasculopathy are the first step to achieve an accurate diagnosis.
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