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Title: [Neurohumoral shifts in brain tumor patients]. Author: Bychkovskiĭ VN, Pleshtis SA, Sobeshchanskiĭ GV. Journal: Zh Vopr Neirokhir Im N N Burdenko; 1978; (6):27-30. PubMed ID: 32711. Abstract: The metabolism of acetylcholine and sympatheticoadrenal substances was studied in patients with cerebral tumors. A significant increase in the content of acetylcholine in blood and cerebrospinal fluid with a simultaneous decrease in the content of inhibitors and sympatheticoadrenal substances were established. A direct dependence between the degree of intracranial hypertension and the level of acetylcholine in blood and cerebrospinal fluid was revealed. Disorders of the metabolism of biologically active substances and their role in the pathogenesis of edema of the brain substantiate pathogenetically the inclusion of cholinolytic and sympathicotonic drugs in the symptomatic treatment of patients with cerebral tumors.[Abstract] [Full Text] [Related] [New Search]