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  • Title: The role of epsilon-aminocaproic acid in reducing bleeding after cardiac operation: a double-blind randomized study.
    Author: Vander Salm TJ, Ansell JE, Okike ON, Marsicano TH, Lew R, Stephenson WP, Rooney K.
    Journal: J Thorac Cardiovasc Surg; 1988 Mar; 95(3):538-40. PubMed ID: 3278170.
    Abstract:
    Sixty patients scheduled for elective coronary artery bypass graft operations were randomly assigned to receive epsilon-aminocaproic acid or placebo to test whether antifibrinolytic therapy would decrease postoperative bleeding. A small but significant decrease in bleeding was observed in the treated group without complications resulting from treatment with epsilon-aminocaproic acid.
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