These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Lack of association between CYP11B2 -344T/C polymorphism and transient ischemic attack in a Chinese population.
    Author: Fan J, Shen Y, Chen B, Xu C, Ye H, Wang J, Zhou W, Sheng Y, Xu F, Yang P.
    Journal: J Int Med Res; 2020 Aug; 48(8):300060520947916. PubMed ID: 32790508.
    Abstract:
    OBJECTIVE: This study investigated whether the CYP11B2 -344T/C polymorphism is correlated with transient ischemic attack (TIA) susceptibility. METHODS: We recruited 100 TIA patients and 100 control subjects and analyzed the CYP11B2 -344T/C polymorphism using restriction fragment length polymorphism (PCR-RFLP). RESULTS: The frequency in TIA patients and controls was 42% compared with 48% for TT genotypes, 51% compared with 45% for TC genotypes, and 7% compared with 7% for CC genotype, respectively. Allele frequencies in TIA patients and controls were 67.5% compared with 70.5% for T-allele and 32.5% compared with 29.5% for C-allele, respectively. No association between the CYP11B2 -344T/C polymorphism and TIA was observed in all comparisons. CONCLUSION: Our data suggest that there was no association between the CYP11B2 -344T/C polymorphism and TIA in a Chinese population.
    [Abstract] [Full Text] [Related] [New Search]