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  • Title: [Effect of acute hypoxia on the renin and erythropoietin activities of the blood serum in rats].
    Author: Kalacheva NM, Zaĭchik AM, Pavlov AD, Morshchakova EF.
    Journal: Biull Eksp Biol Med; 1988 Mar; 105(3):281-3. PubMed ID: 3280049.
    Abstract:
    A comparative study of renin and erythropoietin content in the blood serum of rats with "endocrine" kidneys and changes in their activity following the action of specific erythropoietic stimulus (4-hour hypoxia) has been conducted. The presence of "endocrine" kidneys increased renin and erythropoietin activity in such animals. Acute hypoxia produced further increase in erythropoietin titre in the blood serum, with renin remaining at the same level. Possible differences in the mechanisms of renin and erythropoietin biogenesis in the kidneys are considered.
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