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Title: Yq deletion and failure of spermatogenesis. Author: Hartung M, Devictor M, Codaccioni JL, Stahl A. Journal: Ann Genet; 1988; 31(1):21-6. PubMed ID: 3281566. Abstract: The spermatogenesis of a sterile male carrying a Y long arm deletion was analyzed by meiotic techniques and by light and electron microscopy on testicular biopsies. R-, Q- and C- banding techniques have shown that the Y long arm deletion included the entire heterochromatin and a part of the euchromatic region, with breakpoint between q11.21 and q11.23. The seminiferous tubules showed a sharp decrease in spermatogonia, degenerative phenomena in their nuclei and a spermatogenic block. Abnormal meiotic aspects were observed: pairing failure with atypical diakinesis configurations. These findings confirm the presence of spermatogenesis controlling factors on the distal euchromatic region of the Y long arm.[Abstract] [Full Text] [Related] [New Search]