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  • Title: The chemical characterization of the radioactive products derived from [[3H]PheB1]insulin in the circulation of the rat.
    Author: Davies JG, Offord RE.
    Journal: Biochem J; 1988 Mar 01; 250(2):389-93. PubMed ID: 3281663.
    Abstract:
    1. Gel filtration of rat plasma taken 1 h after subcutaneous injection of [[3H]PheB1]insulin gives three peaks of radioactivity. 2. The material in these peaks was characterized by electrophoresis and chromatography. 3. We conclude that [[3H]PheB1]insulin is rapidly degraded to free tritiated phenylalanine. The phenylalanine is subsequently used for synthesis of plasma proteins de novo.
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