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  • Title: Double blind controlled randomized study on azathioprine efficacy in multiple sclerosis. Preliminary results.
    Author: Milanese C, La Mantia L, Salmaggi A, Campi A, Bortolami C, Tajoli L, Nespolo A, Corridori F.
    Journal: Ital J Neurol Sci; 1988 Feb; 9(1):53-7. PubMed ID: 3281916.
    Abstract:
    The preliminary results of a double blind controlled prospective randomized trial of Azathioprine for therapeutic efficacy in 38 patients with Multiple Sclerosis are reported. Progression of the disease is significantly reduced in Azathioprine-treated group in comparison to Placebo-treated patients, but this effect is reached only after 3 years of treatment (P less than 0.025) regardless of the clinical course and without affecting relapse rate.
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