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  • Title: Bioinformatics Analysis of DNA Methylation Through Bisulfite Sequencing Data.
    Author: Sang F.
    Journal: Methods Mol Biol; 2021; 2198():441-450. PubMed ID: 32822049.
    Abstract:
    DNA methylation plays an important role in the regulation of gene expression as one of the epigenetic modifications. The bisulfite sequencing is widely used to determine the patterns of genomic methylation as a gold standard technology allowing conversion of the unmethylated cytosines to uracils that are represented as Ts in the sequencing reads. This chapter introduces the methodology for analyzing bisulfite sequencing data using various bioinformatics tools.
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