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  • Title: [Effect of Ca2+ on the motility of myosin head in the F-actin-HMM complex].
    Author: Borovikov IuS, Wrotek M, Aksenova NB, Lebedeva NN, Kankol I.
    Journal: Biokhimiia; 1988 Jan; 53(1):97-100. PubMed ID: 3282547.
    Abstract:
    Using polarization microfluorimetry, the effect of Ca2+ on the mode of interaction between heavy meromyosin labeled with 1.5-IAEDANS and F-actin was studied. The results obtained suggest that both the orientation and motility of myosin heads in the F-actin-heavy meromyosin complex depend on Ca2+ concentration. The experimental results are suggestive of the existence of a myosin-coupled regulatory system in skeletal muscles.
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