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  • Title: Increased Intracranial Pressure Without Hydrocephalus Associated With Spinal Cord Tumor: Literature Review.
    Author: Zhou Y, McClelland CM, Lee MS.
    Journal: J Neuroophthalmol; 2021 Mar 01; 41(1):13-18. PubMed ID: 32826715.
    Abstract:
    Spinal cord tumors (SCTs) may rarely cause increased intracranial pressure without hydrocephalus (IICPWH). A review of the English literature published after 1970 revealed 29 cases of IICPWH secondary to SCT. The following data were acquired: demographics, tumor characteristics, ophthalmic and neurological manifestations, and cerebral spinal fluid (CSF) features. We summarize the existing literature regarding various theories of pathophysiology, spinal imaging recommendations, and treatment modalities used in managing such patients. Patients with papilledema who also have neurological signs or symptoms of myelopathy or elevated CSF protein particularly in the setting of an atypical demographic for pseudotumor cerebri should raise a suspicion for a spinal tumor and prompt further investigation with a spinal MRI.
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