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Title: Autoantibodies to the core proteins of hnRNPs. Author: Dangli A, Guialis A, Vretou E, Sekeris CE. Journal: FEBS Lett; 1988 Apr 11; 231(1):118-24. PubMed ID: 3282919. Abstract: A novel autoantibody reacting the the core polypeptides of hnRNP particles has been detected in the serum of a patient with systemic lupus erythematosus (SLE) and Sjögren's syndrome manifestations. Immunoblot analysis, using either rat liver or HeLa nuclear extracts as the antigen source, demonstrated that the autoantibody interacts with a specific subgroup of the core polypeptides of hnRNP particles, namely A2, B1 and B2, but not with A1, C1 and C2.[Abstract] [Full Text] [Related] [New Search]