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  • Title: Imidazole modified Pt(iv) prodrug-loaded multi-stage pH responsive nanoparticles to overcome cisplatin resistance.
    Author: Kang X, Wang Y, Chen Z, Wu Y, Chen H, Yang X, Yu C.
    Journal: Chem Commun (Camb); 2020 Sep 28; 56(76):11271-11274. PubMed ID: 32830841.
    Abstract:
    An imidazole modified Pt(iv) prodrug with a long lipid tail can assemble into multi-stage pH responsive nanoparticles via electrostatic complexation with a negatively charged hydrophilic polymer. This strategy could overcome cisplatin resistance significantly.
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