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  • Title: PTFE versus human umbilical vein in above knee femoro-popliteal bypass. Early results of a randomized clinical trial.
    Author: Aalders GJ, van Vroonhoven TJ, Lobach HJ, Wijffels CC.
    Journal: J Cardiovasc Surg (Torino); 1988; 29(2):186-90. PubMed ID: 3283140.
    Abstract:
    The results of a prospective randomized clinical trial comparing PTFE and HUV grafts in above knee femoro-popliteal reconstruction are presented. A total of 93 limbs were randomized, three patients died in the early postoperative period, leaving 90 (45 PTFE and 45 HUV bypasses) to be analysed. During 18 months of follow-up only 3 HUV grafts occluded in contrast to 15 occluded PTFE grafts. After one year patency rates for HUV were 90% versus 67% for PTFE grafts, after 18 months 86% and 63% respectively. From one year postoperatively onwards these results are statistically and significantly different. When an above knee femoro-popliteal reconstruction is performed and autologous vein is not available or purposely not used, HUV gives better results than PTFE and is the graft of choice.
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