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  • Title: [Panencephalopathy of the Creutzfeldt-Jakob disease type].
    Author: Gertz HJ, Stoltenburg G, Cruz-Sanchez F, Lafuente J, Schopol R.
    Journal: Nervenarzt; 1988 Feb; 59(2):110-2. PubMed ID: 3283576.
    Abstract:
    Creutzfeldt-Jakob disease (CJD) occurring in later life has a duration of about one year. Gait disturbance, myoclonic jerks, dementia and akinetic mutism occur. Post-mortem examination of the brain shows nerve cell loss, gliosis and spongiform changes of the grey matter. Clinical and neuropathological features of a case of the panencephalopathic type of CJD, with additional extensive degeneration of the cerebral white matter, are described. The panencephalopathic type of CJD is characterized clinically by a longer duration and a biphasic course.
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