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Title: Impression cytology detects subclinical vitamin A deficiency. Author: Amedee-Manesme O, Luzeau R, Wittepen JR, Hanck A, Sommer A. Journal: Am J Clin Nutr; 1988 May; 47(5):875-8. PubMed ID: 3284329. Abstract: The vitamin A status of 16 children with normal eyes and liver disease was evaluated by plasma retinol concentration and by liver vitamin A concentration or iv relative-dose-response test. Conjunctival impression cytology was performed on each child. All children with normal vitamin A status had normal conjunctival impression cytology. All children with abnormal vitamin A status had abnormal conjunctival impression cytology despite their seemingly normal clinical ocular examination. These results suggest that impression cytology can identify individuals with physiologically significant, preclinical vitamin A deficiency.[Abstract] [Full Text] [Related] [New Search]