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  • Title: Comparison of saline and streptokinase-streptodornase in the treatment of leg ulcers.
    Author: Forsling E.
    Journal: Eur J Clin Pharmacol; 1988; 33(6):637-8. PubMed ID: 3284754.
    Abstract:
    In 31 patients with leg ulcers the wounds were randomly allocated to treatment either with a solution of streptokinase plus streptodornase in saline or physiological saline alone. The occurrence of pus and debris in the wounds was evaluated by a "blinded" investigator at the initiation of treatment and on Days 5, 10 and 15. In 12 out of 13 patients treated with the streptokinase-streptodornase solution and in 8 out of 16 saline-treated patients the wounds were clean by Day 10.
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