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  • Title: [Effect of prostaglandins I2 and E1 on the cholesterol level in cultured smooth muscle cells from the human aorta].
    Author: Shakhov IuA, Lamaziere JM, Dorian B, Daret D, Larrue J.
    Journal: Biokhimiia; 1988 Feb; 53(2):328-31. PubMed ID: 3285897.
    Abstract:
    Prostaglandins I2(PGI2) and E1(PGE1) (5 X 10(-7) M) reduced by 30% the content of intracellular cholesterol in cultured human aorta smooth muscle cells after 24 hrs of incubation in a medium without fetal calf serum. Total HDL, as well as HDL3 and HDL2b fractions stimulated the effect of prostaglandins on the reduction (by 50%) of cholesterol level.
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