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  • Title: Ultrasonically guided percutaneous and transvaginal follicle aspiration; a comparative study.
    Author: Janssen-Caspers HA, Wladimiroff JW, van Gent I, Alberda AT, Leerentveld RA, Zeilmaker GH, Drogendijk AC.
    Journal: Hum Reprod; 1988 Apr; 3(3):337-9. PubMed ID: 3286680.
    Abstract:
    In this study we compare the efficacy of ultrasonically guided percutaneous oocyte collection for in-vitro fertilization with ultrasonically guided transvaginal oocyte collection. Forty-seven patients were prospectively randomized into two groups. Twenty-four patients underwent percutaneous follicle aspiration and 23 patients underwent a transvaginal puncture. The number of aspirated oocytes per patient showed a statistically significant difference in the two groups: 2.5 for the percutaneous puncture versus 5.2 for the transvaginal procedure. The number of embryos per patient was 2.7 in the transvaginal puncture group versus 1.6 in the percutaneous puncture group. This difference was not statistically significant. The clinical pregnancy rate per patient was 12.5% with the percutaneous approach and 30.4% with the transvaginal technique. This difference was also not statistically significant. Since the transvaginal procedure also creates less discomfort to the patient and is less time-consuming it is concluded that this approach is preferable to the percutaneous puncture technique in obtaining oocytes for in-vitro fertilization.
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