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  • Title: Parkinson's disease: an open label trial of pergolide in patients failing bromocriptine therapy.
    Author: Factor SA, Sanchez-Ramos JR, Weiner WJ.
    Journal: J Neurol Neurosurg Psychiatry; 1988 Apr; 51(4):529-33. PubMed ID: 3288717.
    Abstract:
    Sixty-three patients with Parkinson's disease who failed bromocriptine therapy for various reasons were treated in an open-label trial of pergolide. The data were evaluated in a retrospective manner. Forty-six percent had a good response and tolerated the pergolide. A comparison of the outcomes regarding response and toxicity revealed that bromocriptine and pergolide act differently in individual patients. A trial of pergolide in Parkinsonian patients failing bromocriptine therapy may be therapeutically useful.
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