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  • Title: Approach on chitosan/virgin coconut oil-based emulsion matrices as a platform to design superabsorbent materials.
    Author: Silva SS, Rodrigues LC, Fernandes EM, Gomes JM, Vilas-Boas Â, Pirraco RP, Reis RL.
    Journal: Carbohydr Polym; 2020 Dec 01; 249():116839. PubMed ID: 32933683.
    Abstract:
    The design of innovative pharmaceutical products, able to reach unexplored market niches, requires natural materials use with improved swelling and moisture properties. Herein, chitosan (CHT), a natural polymer, was combined with virgin coconut oil (VCO), a resource extracted from coconut kernels, to develop emulsion-based films for biomedical purposes. The film's properties were tuned by changing VCO concentrations, and the structural, morphological, and physical properties of the films were evaluated. The CHT/VCO-based film morphology showed the presence of VCO droplets at different sizes, both in the surface and inner part. Moreover, the capability to develop CHT/VCO-films as superabsorbent materials was shown. The film extracts cytotoxicity was assessed using human adipose stem cells, and metabolic activity was confirmed. The findings suggest that incorporating a small volume of VCO into the CHT system, superabsorbent materials with the potential to be applied in biomedical devices that require high swelling properties, can be developed.
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