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  • Title: Joule heating-enabled electrothermal enrichment of nanoparticles in insulator-based dielectrophoretic microdevices.
    Author: Malekanfard A, Liu Z, Song L, Kale A, Zhang C, Yu L, Song Y, Xuan X.
    Journal: Electrophoresis; 2021 Mar; 42(5):626-634. PubMed ID: 32935875.
    Abstract:
    Insulator-based dielectrophoresis (iDEP) exploits the electric field gradients formed around insulating structures to manipulate particles for diverse microfluidic applications. Compared to the traditional electrode-based dielectrophoresis, iDEP microdevices have the advantages of easy fabrication, free of water electrolysis, and robust structure, etc. However, the presence of in-channel insulators may cause thermal effects because of the locally amplified Joule heating of the fluid. The resulting electrothermal flow circulations are exploited in this work to trap and concentrate nanoscale particles (of 100 nm diameter and less) in a ratchet-based iDEP microdevice. Such Joule heating-enabled electrothermal enrichment of nanoparticles are found to grow with the increase of alternating current or direct current electric field. It also becomes more effective for larger particles and in a microchannel with symmetric ratchets. Moreover, a depth-averaged numerical model is developed to understand and simulate the various parametric effects, which is found to predict the experimental observations with a good agreement.
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