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  • Title: [Evaluation of the activity of leukocytes during experimental periodontitis in the monkey].
    Author: Gagnot G, Michel JF, Legall E, Merdrignac G, Genetet B.
    Journal: J Biol Buccale; 1988 Mar; 16(1):25-30. PubMed ID: 3294233.
    Abstract:
    Polymorphonuclear leucocytes play an important role in the defense mechanisms and destruction of periodontal tissues. The leucocytes number and activity were compared during an induced periodontitis in 3 Cercopithecus cephus. On day 0, the 3 animals presented a localized marginal gingivitis. On 2 animals a severe marginal periodontitis was induced unilaterally: 42 days later leucocytes were sampled in the peripheral blood, in the gingival blood and in the gingival sulcus on the experimental and control sites as well as on the 2 hemijaws of the control animal. For each sample, a leucocyte count and a chemiluminescence test were done. Different results related to the disease severity were obtained with these tests for gingival blood and sulcular fluid.
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