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Title: [Effect of acupoint application therapy at different timing points on gastrointestinal function recovery and heart rate variability after laparoscopic resection of colorectal cancer]. Author: Zhi MW, Dai XJ, Jiang ZW, Xu SS, Li M, Xie RY. Journal: Zhongguo Zhen Jiu; 2020 Sep 12; 40(9):947-52. PubMed ID: 32959589. Abstract: OBJECTIVE: To observe the effect of acupoint application therapy at different timing points on the gastrointestinal function recovery and heart rate variability (HRV) after laparoscopic resection of colorectal cancer under the instruction of enhanced recovery after surgery (ERAS). METHODS: A total of 105 patients for the selective laparoscopic resection of colorectal cancer were selected and randomized into a preoperative acupoint application group (35 cases, 3 cases dropped off), a postoperative acupoint application group (35 cases, 1 case dropped out) and a control group (35 cases, 2 cases dropped off). In the control group, ERAS interventions were provided, such as health education, fluid supplementation and multi-mode analgesia. On the base of the treatment as the control group, in the preoperative acupoint application group and the postoperative acupoint application group, 3 days before operation and 6 h after operation, the acupoint application therapy was given respectively. The acupoints were Zusanli (ST 36), Shangjuxu (ST 37), Sanyinjiao (SP 6), Neiguan (PC 6) and Xiajuxu (ST 39). The acupoint application was exerted for 6 h each time, once daily till the first postoperative exhaust and defecation presented. It was to observe the time of the first postoperative exhaust, defecation and food intake, the score of visual analogue scale (VAS) 1 to 3 days after operation, the total score of gastrointestinal symptom rating scale (GSRS) before and 1 week after operation, as well as the related indicators of HRV [standard deviation of NN intervals (SDNN) and the ratio of low-frequency power and high frequency power (LF/HF)] in the three groups successively. Besides, the adverse reactions were recorded during intervention in the three groups. RESULTS: Compared with the control group, the time of the first postoperative exhaust and the time of the first postoperative defecation were all earlier in the preoperative acupoint application group and the postoperative acupoint application group respectively (P<0.05), and VAS scores 1 to 3 days after operation and total GSRS scores 1 week after operation were all reduced (P<0.05); the time of first food intake was earlier after operation (P<0.05), and SDNN and LF/LF were increased 1 day and 3 days after operation in the preoperative acupoint application group (P<0.05). Compared with the postoperative acupoint application group, in the preoperative acupoint application group, the time of the first postoperative exhaust and the time of the first postoperative defecation were all earlier (P<0.05), VAS scores were reduced in 1 to 3 days after operation (P<0.05), and SDNN 1 day and 3 days after operation and LF/HF 1 day after operation were all increased (P<0.05). No adverse reaction was detected in patients of the three groups. CONCLUSION: Under the instruction of ERAS, the preoperative acupoint application effectively promotes the postoperative gastrointestinal function recovery, improves HRV and autonomous nerve function in the patients after laparoscopic resection of colorectal cancer. The therapeutic effect of this therapy is better than the postoperative acupoint application. 目的:在加速康复外科(ERAS)理念指导下,观察不同时机穴位贴敷对结直肠癌根治术后胃肠功能恢复及心率变异度(HRV)的影响。方法:选取拟择期行腹腔镜下结直肠癌根治术患者105例,随机分为术前贴敷组(35例,脱落3例)、术后贴敷组(35例,脱落1例)和对照组(35例,脱落2例)。对照组患者予健康宣教、补液、多模式镇痛等ERAS相关干预;在对照组基础上,术前贴敷组、术后贴敷组分别从术前3 d、术后6 h开始穴位贴敷干预,穴取足三里、上巨虚、三阴交、内关、下巨虚,每次6 h,每天1次,至术后首次出现排气或排便即停止干预。观察3组患者术后首次排气、排便及进食时间;术后1~3 d视觉模拟量表(VAS)评分;术前、术后1周胃肠道症状分级量表(GSRS)评分总分;术前,术后1、3 d 心率变异度相关指标[全部窦性心搏RR间期的标准差(SDNN)、低频功率/高频功率(LF/HF)]变化,并记录 3组患者干预期间的不良反应。结果:术前贴敷组及术后贴敷组患者术后首次排气时间、首次排便时间均早于对照组(P<0.05),术前贴敷组及术后贴敷组术后1~3 d VAS评分及术后1周GSRS评分总分均低于对照组(P<0.05),术前贴敷组术后首次进食时间早于对照组(P<0.05),术后1、3 d SDNN、LF/HF均高于对照组(P<0.05)。术前贴敷组术后首次排气时间、首次排便时间均早于术后贴敷组(P<0.05),术后1~3 d VAS评分均低于术后贴敷组(P<0.05),术后1、3 d SDNN及术后1 d LF/HF均高于术后贴敷组(P<0.05)。3组患者均未出现不良反应。结论:在加速康复外科理念指导下,术前穴位贴敷能有效促进行腹腔镜下结直肠癌根治术患者术后胃肠功能恢复,提高心率变异度及自主神经功能,疗效优于术后穴位贴敷。.[Abstract] [Full Text] [Related] [New Search]