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Title: Diet and nutritional factors in the aetiology of colon cancer (review). Author: Sian MS. Journal: Anticancer Res; 1987; 7(3 Pt A):293-300. PubMed ID: 3296943. Abstract: Epidemiological studies suggest that diet may be a major risk factor in the aetiology of colon cancer. Total fat, meat, animal protein and dietary fibre have received most attention. A high-fat - high-protein diet leading to increased faecal steroids has been implicated, but no active carcinogen derived from these has been isolated from human faeces. Alternatively, a refined, low fibre diet with decreased faecal bulk leads to increased large bowel concentration of carcinogens of co-carcinogens which contribute to the development of a malignant tumour. The aetiology of colonic cancer is probably multifactorial but a diet low in animal fat and protein and abundant in vegetables containing vitamin A and lignans may protect against colon cancer.[Abstract] [Full Text] [Related] [New Search]