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  • Title: [Participation of leu-enkephalin in regulating carbohydrate metabolism].
    Author: Zoloev GK.
    Journal: Biull Eksp Biol Med; 1987 May; 103(5):515-7. PubMed ID: 3297184.
    Abstract:
    The experiments have been performed on 166 white male rats with a mass of 180-220 g. It has been revealed that leucine-enkephalin and its synthetic analogs prevent an increase in glucose blood levels and a decrease in glycogen liver levels caused by adrenaline and parathyroid hormone. At the same time the enkephalins inhibit the secretory activity of pancreatic beta-cells. The mechanisms of opioid peptide effect on carbohydrate metabolism are discussed.
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