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  • Title: Chromosome localization of the human renin gene (REN) by in situ hybridization.
    Author: McGill JR, Chirgwin JM, Moore CM, McCombs JL.
    Journal: Cytogenet Cell Genet; 1987; 45(1):55-7. PubMed ID: 3297510.
    Abstract:
    Previous studies by Southern blot analysis of human X mouse somatic cell hybrids localized the renin gene to region p21----qter of human chromosome 1. Using a DNA insert encoding exons 2-5, the renin gene was mapped to human chromosome bands 1q25----q32 by in situ hybridization. The sublocalization of the renin gene will facilitate subsequent detailed linkage analysis of human chromosome 1.
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