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  • Title: Intrahepatic cholestasis in acute viral hepatitis: a double-blind trial with dihydroxydibutylether in comparison with placebo.
    Author: Marchettini G, Corsini P, Massimini G.
    Journal: Drugs Exp Clin Res; 1987; 13(1):51-6. PubMed ID: 3297594.
    Abstract:
    The authors studied the effectiveness of a choleretic drug, dihydroxydibutylether (DHBE), 900 mg daily, in patients with acute viral hepatitis and intrahepatic cholestasis. The four-week, double-blind and placebo-controlled trial showed a more rapid return to normal bilirubin and fasting and post-prandial biliary acid values and plasma transaminases levels in the DHBE-treated group of patients.
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