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  • Title: [Autoantibody diagnosis in Wegener's granulomatosis].
    Author: Lüdemann G, Lüdemann J, Nölle B, Gross WL.
    Journal: Immun Infekt; 1987 Apr; 15(2):74-6. PubMed ID: 3298018.
    Abstract:
    Anticytoplasmic antibodies (ACPA) against myelomonocytic cells were demonstrable in 54 of 72 patients with Wegener's granulomatosis (WG). Other autoantibodies (including ANA, AMAb, RF and anti-ENA) were only found in a low frequence and titre. The presence of ACPA correlated with the severity and activity of the disease. These results demonstrated that ACPA is a valuable tool to establish the diagnosis and to monitor disease activity in WG.
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