These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: 5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.
    Author: Byerley WF, Judd LL, Reimherr FW, Grosser BI.
    Journal: J Clin Psychopharmacol; 1987 Jun; 7(3):127-37. PubMed ID: 3298325.
    Abstract:
    Alterations in serotonin metabolism may be an important factor in the etiology and treatment of depression. In this regard, 5-hydroxytryptophan (5-HTP), a serotonin precursor, has been given to patients with depression. Although a review of these studies suggests that 5-HTP possesses antidepressant properties, additional trials are clearly indicated. Following a discussion of the pharmacology of 5-HTP, the authors highlight adverse effects associated with its administration to depressed patients, neurologic subjects, and normal individuals. Relatively few adverse effects are associated with its use in the treatment of depressed patients.
    [Abstract] [Full Text] [Related] [New Search]