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  • Title: Renal magnesium wasting in two families with autosomal dominant inheritance.
    Author: Geven WB, Monnens LA, Willems HL, Buijs WC, ter Haar BG.
    Journal: Kidney Int; 1987 May; 31(5):1140-4. PubMed ID: 3298795.
    Abstract:
    Hypomagnesemia due to isolated renal magnesium loss was demonstrated in two unrelated families with autosomal dominant mode of inheritance. Magnesium infusions performed in two patients showed not only a reduced renal magnesium threshold but also a lowered renal tubular maximum for magnesium. All members of both families who presented with hypomagnesemia had also a lowered excretion of calcium in the urine, presumably as a consequence of increased reabsorption in Henle's loop.
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