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  • Title: Systemic angioendotheliomatosis of the lung.
    Author: Remberger K, Nawrath-Koll I, Gokel JM, Haider M.
    Journal: Pathol Res Pract; 1987 Apr; 182(2):265-74. PubMed ID: 3299327.
    Abstract:
    Systemic angioendotheliomatosis is a very rare malignant disease characterized by intravascular neoplastic proliferation of reticuloendothelial cells. According to the clinical features three different types of prognostic value can be distinguished: Exclusive skin involvement; Progressive skin lesions disseminating to internal organs; Aggressive and lethal type affecting primarily internal organs. Until now about 60 cases of systemic angioendotheliomatosis have been reported in the literature. Here we describe the first well-documented case with almost isolated lung involvement. The presentation of morphologic and clinical signs and differential-diagnostic considerations are followed by a critical review of the literature.
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