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  • Title: Delayed-type allergy against various insulin preparations including human semisynthetic insulin.
    Author: Würzburger MI, Prelević GM, Despotović N, Vucković S, Brkić SD, Bozović M, Nastić-Mirić D.
    Journal: Ann Allergy; 1987 Jul; 59(1):44-7. PubMed ID: 3300437.
    Abstract:
    The authors present a patient with delayed-type allergy against insulin preparations of different species including highly purified monocomponent insulin and human semisynthetic insulin. Positive results for cutaneous delayed-type hypersensitivity and for lymphocyte blastogenesis suggested a type IV immunopathogenic reaction. Intradermal tests performed with various components of insulin preparations revealed delayed-type allergy to insulins of different species (bovine, porcine and human) but not to any of the other components.
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