These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Sensitivity of dimorphic Candida albicans cells to polyene antibiotics and their combinations with other biologically active substances].
    Author: Araviĭskiĭ RA, Potyl'chanskaia OL.
    Journal: Antibiot Med Biotekhnol; 1987 May; 32(5):354-7. PubMed ID: 3300522.
    Abstract:
    It was shown that polyenic antibiotics and their combinations with some other antifungal and antibacterial agents prevented transformation of the C. albicans yeast phase into the tissue one. Moreover, the fungus tissue form proved to be more sensitive than the yeast form to the drugs and especially to their combinations. The in vitro findings were confirmed by the in vivo studies. Combinations of amphotericin B with methacycline, rifampicin, 5-fluorocytosine or polymyxin B were more efficient than the polyene alone. Summation of the drug antifungal effects provided a 4-fold decrease in the polyene quantity required for administration to experimental animals.
    [Abstract] [Full Text] [Related] [New Search]