These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Photocatalytic Generation of π-Allyltitanium Complexes via Radical Intermediates.
    Author: Li F, Lin S, Chen Y, Shi C, Yan H, Li C, Wu C, Lin L, Duan C, Shi L.
    Journal: Angew Chem Int Ed Engl; 2021 Jan 18; 60(3):1561-1566. PubMed ID: 33009696.
    Abstract:
    The addition of π-allylmetal complexes to carbonyls is the most important route to homoallylic alcohols. This study reports the first photocatalytic generation of π-allyltitanium complexes by a radical strategy. This novel strategy enables the three-component allylation of carbonyls with 1,3-butadiene, providing rapid access to valuable homoallylic alcohols (over 60 examples). The exceptional regio- and diastereoselectivity provided by dual photoredox/Ti catalysis is comparable to that of the Cr-catalyzed Nozaki-Hiyama-Kishi allylation reaction.
    [Abstract] [Full Text] [Related] [New Search]