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  • Title: CV-1, a new antibiotic produced by a strain of Streptomyces sp. I. Fermentation, isolation and biological properties of the antibiotic.
    Author: Ichimura M, Koguchi T, Yasuzawa T, Tomita F.
    Journal: J Antibiot (Tokyo); 1987 Jun; 40(6):723-6. PubMed ID: 3301772.
    Abstract:
    A new antibiotic, CV-1, was isolated from the culture broth of a Streptomyces sp. by various chromatographies. CV-1 showed antibacterial activity against Escherichia coli in cooperation with spiramycin, a macrolide antibiotic. The mode of action of CV-1 seemed to be the inhibition of lipopolysaccharide synthesis.
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