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  • Title: Extramedullary Hematopoiesis in the Dura Mater During Treatment of a CNS Embryonal Tumor.
    Author: Ganapathi SS, Havard ME, Ferguson M, Cole BL, Millard NE, Vitanza NA.
    Journal: J Pediatr Hematol Oncol; 2021 Nov 01; 43(8):e1217-e1219. PubMed ID: 33031159.
    Abstract:
    Extramedullary hematopoiesis (EMH) is hematopoiesis occurring outside of the bone marrow. It has been reported to develop in abdominal organs or lymph nodes after chemotherapy. Here, the authors describe a patient with a localized central nervous system embryonal tumor who, during intensive chemotherapy, developed dural nodules. Biopsy revealed these nodules to be EMH. Without a pathologic diagnosis, this may have been considered disease progression, altering the patient's treatment plan. This report intends to serve as a reminder that EMH should be included in the differential diagnosis of suspicious lesions and highlights the importance of their biopsy because of potential management implications.
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