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  • Title: Effects of extracellular osmolality on renin release and on the ultrastructure of the juxtaglomerular epithelioid cell granules.
    Author: Skøtt O, Taugner R.
    Journal: Cell Tissue Res; 1987 Aug; 249(2):325-9. PubMed ID: 3304649.
    Abstract:
    Superfusion with hypoosmotic solutions stimulates renin release from rat epithelioid cells adherent to isolated glomeruli. This stimulatory effect may be related to the observed swelling of the secretory granules; the swelling may markedly increase the probability of pre-exocytotic fusions between the granule and cell membranes, and consequently increase the frequency of exocytotic events.
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